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Fighting antibiotic resistance with knowledge and open science - in classroom and beyond[Bearbeiten]


Antimicrobial resistance (AMR) is a major public health concern, yet there is little public engagement when it comes to tackling this problem. Using the open science tools, this project aims to share the current understanding of the AMR problem and solutions with the young people (life science and veterinary medicine students) in three countries with different rates of antibiotic use, engage them into the original research that will contribute new knowledge on AMR, promote international collaboration on an important public health issue, and encourage the students to become the “AMR ambassadors” in their respective communities and future professional activities, thereby ensuring the maximum impact of knowledge.


Antimicrobial resistance (AMR) is a global public health threat: it is estimated that by 2050, it will claim lives of 300 million people, surpassing cancer mortality. Rise of “superbugs” - bacteria that are resistant to several antimicrobial agents - means that trivial medical interventions will soon become once again high-risk, since no efficient antimicrobial chemotherapy is available. Yet there is little awareness among the general population and even some professionals whose job involves use of antimicrobials about the extent of this problem and how their actions could contribute to it.

The overall goal of this project is to engage early and show the importance of the prudent use of antibiotics to the students, who will in the future have the power to decide when to apply antimicrobials and work closely with and influence communities, where antimicrobials are used. Specifically, I aim to develop a graduate-level course where the life science and veterinary medicine students would (i) be educated about the current situation with the AMR in the environment, the driving forces and the mitigation strategies; (ii) conduct collaborative international original research on the topic, and (iii) be encouraged to become AMR awareness ambassadors in their communities and future professional activities.

I will create an international online course, where local life science/ veterinary medicine students would first be given online video lectures and tutorials about AMR, followed by the group work in the respective countries, where the students would work out the contributing factors to AMR depending on the strength of the regulations in regard to antibiotic use: strict, intermediate, low. The students will work with open science resources to identify data on national antibiotic use regulations, sales data and AMR incidence. The data will be deposited into the open science database, while the results will be published in open access journals. The students will also be instructed to serve as the “AMR awareness ambassadors” and continue the international collaboration after the course ends.




  • Name: Olga Makarova
  • Institution: Freie Universität Berlin
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